In mid-May 2004, a new insect-resistant cotton transgenic double-value gene-resistant cotton, Xinmian 38, was successfully developed in Shanxi Province by the Institute of Microbiology, Shanxi Academy of Agricultural Sciences and the Institute of Microbiology, Chinese Academy of Sciences. A transgenic insect-resistant cotton with independent intellectual property rights. Transgenic double-resistance insect-resistant cotton is constructed by artificially synthesizing the monovalent Bt cotton gene and a protease inhibitor and constructing them simultaneously. At the same time, it is introduced into cotton cells for dual purpose of insect killing. Its successful research has not only improved the production efficiency of cotton. It has added new vitality to the replacement of insect-resistant cotton varieties in Shanxi Province, at the same time, it has increased the diversity of insect-resistant cotton genes in China and also provided new germplasm resources for cross-breeding of insect-resistant cotton in China.