Apple tree rot disease is a serious hazard to the tree. If it is not controlled in time, it will lead to the death of the main branch or trunk. In recent years, some fruit growers in Fengjing Township, Shanting District, Zaozhuang City, Shandong Province have tried potassium cyanide-potassium permanganate solution to control apple tree rot disease. The drug has strong bactericidal power, good permeability, stable properties, rapid formation of callus, and resistance to rain erosion. According to the experiment, the cure rate was as high as 96.4%; in addition, it also had certain preventive and therapeutic effects on apple stem rot, brown rot, and calcium, copper and manganese trace element deficiency. The formula is as follows: 1kg of copper sulfate, 2kg of quicklime, proper amount of potassium permanganate and 8g of motor oil. Put 0.1% potassium permanganate into the oil and mix well, then add quicklime and copper sulfate in order to use. In 10-12 months of each year or March-April of the following year, use a sharp knife to scrape off the skin of the main branch of the fruit tree or the diseased lice on the main trunk to a depth of xylem, and cut the surrounding fine skin obliquely by 1 cm- 2cm. The cut surface needs to be smooth and clean, with a slope of 45-60, and the sickle should be scraped into a diamond or oval shape. Then use a small brush to apply the liquid with a small brush on the scraped sickle. The spread should be more than 2cm around the sickle. Ask to scrape one piece and apply it again after 2 weeks. When smearing must be uniform and detailed.