Vaccine: flu vaccine can inhibit heart disease

Release date: 2014-10-27

Recent studies have found that influenza vaccines have a protective effect on heart disease and can reduce the risk of heart disease. The study was first published in the journal Vaccine, which clarified this phenomenon from a molecular perspective. Scientists have shown that it can be used directly to prevent heart disease.

Heart disease is the leading cause of death worldwide. People can reduce the risk of heart disease by eating a healthy diet, exercising and quitting smoking. However, no cardiac vaccine has been developed so far.

Previous clinical studies have shown that people receiving seasonal flu vaccines are also beneficial for the protection of heart disease. The risk of heart disease in the population after immunization this year is 50% lower than that of people who have not received vaccination. The exact mechanism of this protection is still unknown.

This new study reveals for the first time the principle of this mechanism, which is the process by which the flu vaccine stimulates the immune system to produce antibodies that open the cell. These processes cause the production of molecules that protect the heart. The researchers said that based on the results, a new vaccine to protect heart disease could be developed.

"Although the protective effect of influenza vaccine on heart disease is well known, there is little detailed information on its mechanism of action. The mechanism of action in our study will use vaccines to treat heart disease, and we plan to further study this issue. Dr. Veljkovic said.

The researchers discovered a protein called the bradykinin 2 receptor (BKB2R), a protein involved in the process of protecting the heart's cells. After the flu vaccination, the body produces antibodies that prevent the heart disease from opening up the protein. The researchers analyzed 14 influenza virus vaccines in use and found that the four vaccines could be used as potential heart disease vaccines.

“The rate of flu vaccination is very low, even in developed countries,” Dr. Veljkovic added. “We hope that our results will encourage more people to vaccinate before the flu season begins.”

Source: Bio Valley

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