German scientists use genetically modified tobacco to fight against superbugs

According to the German "World News" reported on the 4th, many pathogens can no longer be destroyed by antibiotics, because they are resistant and rapid, but phage are their natural enemies. Researchers hope to accumulate this particular virus in tobacco genetically altered and use them to make new and effective drugs.
It has been reported that many serious diseases of humans are caused by bacteria, one of which is S. pyogenes which can cause various respiratory and skin diseases. The natural enemy of this bacterium is the bacteriophage, a special virus that can invade pathogens and break it down at the end of the virus's reproductive cycle, and so-called cytolysins can trigger this process.
Researchers at the Max Planck Institute for Molecular Plant Physiology, led by Ralph Burke, successfully implanted the cytolysin gene into the chloroplast of tobacco to make a large amount of cytolysin.
"The cytolysin is more than 70% of the total protein in the plant," said research team member Melanie Ey. In addition, cytolysins are stable in the face of degrading enzymes - which may be one of the reasons for their large proportion of total plant protein.
The use of viruses to destroy bacteria is not a new method. As early as the beginning of the last century, people began experimenting with bacteriophage to eliminate bacteria. However, the manufacture and purification of antibacterial viral proteins in plants provides an innovative solution for the elimination of resistant bacteria.

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